Alternating and Direct Current Stimulation for Neuropathic Eye Pain
Eye Pain, Neuropathy, Optic, Cerebral Injury
About this trial
This is an interventional treatment trial for Eye Pain
Eligibility Criteria
Inclusion Criteria: persistent eye pain for at least 6 months average eye pain intensity of 4 or more on a 0-10 numerical rating scale naive to transcranial stimulation eye pain having neuropathic-like characteristics Exclusion Criteria: contraindication to transcranial stimulation (i.e., pacemaker, cardioverter defibrillator, neuro-stimulation (brain or spinal cord), bone growth stimulations, indwelling blood pressure monitors, epilepsy, pregnancy) presence of ocular diseases that are the likely cause of pain (i.e., corneal and conjunctival scarring, corneal edema, uveitis, iris transillumination defects, etc.) current participation in another study with an investigational drug or device within one month prior to screening
Sites / Locations
- Eye Clinic, University Hospital in LinköpingRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Transcranial alternating current stimulation
Transcranial direct current stimulation
Transcranial alternating current stimulation (tACS) device using 50x70 mm electrodes that are placed bilaterally between EEG coordinates C3/C5 for left hemisphere and C4/C6 for right hemisphere (corresponding to S1 and M1 of the eye). The alternating current electrodes are in-phase and have the same peak to peak stimulation 3mA, for 30 minutes duration at 10Hz. An impedance value under 15 ohms is required at all times to ensure patient comfort and safety.
Transcranial direct current stimulation (tDCS) device using 50x70 mm electrodes that has the anodal electrode placed contralateral to most prominent ocular pain or, in the case of bilateral pain symptoms, contralateral to the dominant hand between EEG coordinates C3/C5 for left hemisphere and C4/C6 for right hemisphere (corresponding to S1 and M1 of the eye), and the cathode placed on the patient's upper arm. A current peaking at 3mA will ramp up for 20 secs and be delivered for a total of 20 minutes, thereafter, ramping down for 20s. An impedance value under 15 ohms is required at all times to ensure patient comfort and safety.