Unlimited or Restricted Fluid Intake in Patients With Heart Failure
Heart Failure
About this trial
This is an interventional prevention trial for Heart Failure focused on measuring Quality of life, Intervention, Thirst distress, Symptoms, Physical capacity, Hospital readmissions, Lung ultrasound, Fluid intake, B-lines, NT-ProBNP, Heart failure, Fluid restriction
Eligibility Criteria
Inclusion Criteria: Diagnosed with heart failure with reduced ejection fraction (EF <50%) within 3 months hospitalized due to HF deterioration at Karolinska University Hospital at the in-hospital cardiology wards. Ability to provide informed consent. Exclusion Criteria: Reversible cause of HF (thyroid disorders, severe anemia, etc.) Hyponatremia at baseline (sodium < 130 mmol/L) Kidney function measured with eGFR where eGFR of < 30mL/min/1.73m2 at baseline Scheduled cardiac surgery within 3 months Recent (within 3 months) coronary intervention (percutaneous coronary intervention or coronary artery bypass graft surgery) Comorbidity for which fluid restriction is advised Life expectancy < 6 months Ongoing investigation for eligebility of heart transplantation and/or LVAD Pregnancy or planned pregnancy Particiaption in another ongoing clinical trial
Sites / Locations
- Karolinska University Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Unlimited fluid intake
Restricted fluid intake
Patients have no restrictions of fluid intake
Patients have restrictions in fluid intake of 1500 ml/day