The Impact of Myomectomy on IVF Outcomes
Myoma;Uterus, IVF, Surgery
About this trial
This is an interventional treatment trial for Myoma;Uterus
Eligibility Criteria
Inclusion Criteria: Female aged between 20-40 years old. Primary or secondary infertility consisting of following factors rather than uterine factors: male factors, ovulation disorders, fallopian tube factors, endometriosis, other non-uterine factors including infertility with unexplained reason. Myoma: FIGO type 4-6 discovered by MRI with the maximum diameter surgically targeted between 4-6cm; Single myoma, or multiple myomas with non-surgically targeted intramural or subserous myoma(s) < 2cm in maximum diameter. Justifying the IVF criteria and willing to undergo IVF. Exclusion Criteria: Not meeting all the inclusion criteria. Complicated with infertility factors of uterine factors or diseases, including adenomyosis, endometrial adhesion, endometritis, submucous myoma. However, resectable endometrial polyps need not be excluded. Complicated with malignancies or borderline tumors of the reproductive tract Complicated with other malignancies not been treated or still being treated. Complicated with active pelvic inflammatory disease. Previously receiving cytotoxic therapy or abdominal-abdominal chemoradiotherapy. Previous uterine body surgery, including but not limited to: myomectomy, resection for adenomyosis lesions, uterine artery embolization, uterine tumor coagulation (high energy focused ultrasound or electrocoagulation, hysteroscopically myomectomy. However, diagnostic hysteroscopy, diagnostic curettage and polypectomy need not be excluded. No willing to undergo IVF. Unable to be followed-up.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
myomectomy group
control group
The study group received IVF after myomectomy.
The control group was directed to IVF after the routine evaluation, probably including diagnostic laparoscopy.