Role of Intermittent Exogenous Ketosis in the Physiological and Muscular Adaptive Response to Endurance Training
Exercise Adaptations
About this trial
This is an interventional basic science trial for Exercise Adaptations focused on measuring ketone bodies, Exercise adaptations, Sleep
Eligibility Criteria
Inclusion Criteria: Physically fit and regularly involved in physical activity (2-5 exercise sessions of > 30min per week) Good health status confirmed by a medical screening VO2max higher than 50 ml.min-1.kg-1 Body Mass Index (BMI) between 18 and 25 Normal sleep pattern as assessed by the Pittsburgh Sleep Quality Index (PSQI, appendix 2) Exclusion Criteria: Any kind of injury/pathology that is a contra-indication to perform high-intensity exercise Intake of any medication or nutritional supplement that is known to affect exercise performance or sleep Intake of analgesics, anti-inflammatory agents, or supplementary anti-oxidants, from 2 weeks prior to the start of the study. Night-shifts or travel across time zones in the month preceding the study Blood donation within 3 months prior to the start of the study Smoking More than 3 alcoholic beverages per day or more than one glass if wine per day Involvement in elite athletic training at a semi-professional or professional level Any other argument to believe that the subject is unlikely to successfully complete the full study protocol
Sites / Locations
- Exercise Physiology Research Group
Arms of the Study
Arm 1
Arm 2
Placebo Comparator
Experimental
Control group
Experimental groep
Placebo is provided
Ketone ester is provided