Amoxicillin Plus Metronidazole in Periodontal Maintenance
Periodontitis, Periodontal Pocket
About this trial
This is an interventional treatment trial for Periodontitis focused on measuring amoxicillin, dental scaling, metronidazole, periodontal maintenance, periodontitis, root planing
Eligibility Criteria
Inclusion Criteria: individuals under a PMT program monitored over ~13 years of consecutive recall visits (from August 2009 to May 2023). individuals reclassified as stage III and IV periodontitis not having presented the following clinical endpoint in two consecutive PMT visits - presence of ≤4 sites with PD ≥5 mm non-diabetics non-smokers no antibiotic use for any purpose within 3 months prior to entering the study Exclusion Criteria: pregnant or lactating women smokers presence of systemic diseases that could affect the progression of periodontitis long-term administration of anti-inflammatory drugs, need for antibiotic premedication for routine dental therapy and allergy to metronidazole or amoxicillin
Sites / Locations
- Federal University of Minas Gerais, Dental School
Arms of the Study
Arm 1
Arm 2
Placebo Comparator
Experimental
control
antibiotics
1) scaling and root planing (SRP) plus systemic administration of placebo (n=25)
2) scaling and root planing (SRP) plus systemic administration of amoxicillin and metronidazole (n=25).