Umbilical Cord Mesenchymal Stem Cell Improve Cardiac Function on ST-elevation Myocardial Infarction (STEMI) Patients
ST Elevation Myocardial Infarction
About this trial
This is an interventional treatment trial for ST Elevation Myocardial Infarction focused on measuring Umbilical Cord Mesenchymal Stem Cell, ST Elevation Myocardial Infarction, Infarct Size, Left Ventricular Ejection Fraction, IL-10, VEGF, Galectin 3, GATA-4, Beclin 1, Major Cardiac Adverse Events
Eligibility Criteria
Inclusion Criteria: Patients with STEMI treated with primary PCI maximum 12 hours after onset of chest pain Exclusion Criteria: Patients with history of coronary artery bypass grafting surgery Patients with history of heart failure before admission Patients with cardiogenic shock Patients with cancer disease Patients with malignant arrythmia Patients with chronic kidney disease Patients with haemostasis disorder Patients with infection Patients with stroke
Sites / Locations
- Cipto Mangunkusumo Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
UC-MSC
Control
Patients assigned in UC-MSC intervention group will get Umbilical Cord Mesenchymal Stem Cell transplantation
Patient assigned in control group doesn't get Umbilical Cord Mesenchymal Stem Cell transplantation. However, they will be fully treated based on European Society of Cardiology (ESC) guidelines