Feasibility, Acceptability and Directional Signal Effect on Blood Folate Levels of Iodized Salt Fortified With Folic Acid: Clinical Study (FASALT)
Neural Tube Defects, Folic Acid Deficiency, Fortification
About this trial
This is an interventional prevention trial for Neural Tube Defects focused on measuring Serum folate
Eligibility Criteria
Inclusion Criteria: women consumes salt Exclusion Criteria: pregnant or intends to become pregnant in next 6 months
Sites / Locations
- University of Alabama at Birmingham
Arms of the Study
Arm 1
Experimental
Salt with folic acid and iodine
Intervention is intake of double fortified salt with folic acid and iodine (DFS). We will ask the participants to substitute their current salt with the study saltshaker and use it when preparing food or when eating out. We estimate minimum daily intake from salt consumption by participants will be 200 micrograms (µg) of folic acid per serving. Serving is 2g of salt. Participants will be given portion suggestions: 1/2 teaspoon or 2-3 pinches or 8-10 shakes/5 times a day. Containers (125g) will be weighted at the beginning and end of 1 month. We will ask each day if woman cooked/used the salt for herself only or to list number of people each day. Participants will also agree to complete either daily paper salt log. A commercially available salt that is fortified with folic acid has been provided by AlpenJodSalz produced by Sudwestdeutsche Salzwerk. For 30 participants, we will need 30 containers.