Sensitivity of Angiotensin II Type II Receptors in Women Following Preeclampsia
Preeclampsia Postpartum
About this trial
This is an interventional basic science trial for Preeclampsia Postpartum
Eligibility Criteria
Inclusion Criteria: women who had preeclampsia and women who did not have preeclampsia 12 weeks to 5 years postpartum 18-45 years old Exclusion Criteria: history of hypertension or metabolic disease before pregnancy history of gestational diabetes skin diseases current tobacco use current antihypertensive medication statin or other cholesterol-lowering medication currently pregnant or planning to become pregnant body mass index less than 18.5 kg/m2 allergy to materials used during the experiment.(e.g. latex), known allergy to study drugs
Sites / Locations
- University of IowaRecruiting
Arms of the Study
Arm 1
Experimental
assessment of microvascular function
The investigators use intradermal microdialysis to deliver compound 21 and L-NAME to the cutaneous microvasculature