Treatment for Painful Diabetic Neuropathy
Painful Diabetic Neuropathy
About this trial
This is an interventional treatment trial for Painful Diabetic Neuropathy focused on measuring controlled transcranial magnetic stimulation, painful diabetic neuropathy, pain, neuroplasticity
Eligibility Criteria
Inclusion Criteria: A diagnosis of painful diabetic neuropathy (pDN) Exclusion Criteria: a known history of moderate to severe chronic pain other than pDN daily use of opioids prior to the pDN diagnosis contraindications to TMS known psychological diagnosis affecting comprehension and inability to participate in the study
Sites / Locations
- McMaster University
Arms of the Study
Arm 1
Arm 2
Active Comparator
Sham Comparator
Active cTMS
Sham cTMS
Controlled Transcranial Magnetic Stimulation (cTMS) will be delivered at 10 Hz, 1500 pulses targeting the hand representation of the left primary motor cortex. cTMS delivery will require ~9 min to complete. This intervention will be performed approximately 5 days per week for 2 weeks. In addition, participants will experience their standard medical care.
Sham cTMS will be delivered at as a placebo control. It is important to note that from the participant perspective, the sham stimulation will feel and sound identical to active cTMS. This will be performed approximately 5 days per week for 2 weeks. In addition, participants will experience their standard medical care.