Different Autologous Products in The Treatment of Intrabony Defects
Periodontal Pocket
About this trial
This is an interventional treatment trial for Periodontal Pocket focused on measuring Autologous bone graft, concentrated growth factor, platelet-rich fibrin
Eligibility Criteria
Inclusion Criteria: no systemic disease presence of two-wall intrabony defects with radiographic depth ≥3 mm presence of at least four intrabony defects, one in each quadrant (in molar and premolar regions) pocket depth ≥5mm no periodontal treatment within past 6 months Exclusion Criteria: Smoking Having a systemic disease that may affect the treatment results such as uncontrolled diabetes, metabolic bone diseases, hematological disorders, radiotherapy in the head and neck region, kidney disease, Being in pregnancy or breastfeeding period,
Sites / Locations
- Ahmet Cemil TALMAC
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Active Comparator
Active Comparator
Active Comparator
Active Comparator
CONTROL GROUP (GROUP 1)
GROUP 2
GROUP 3
GROUP 4
Only open flap debridement (OFD): Conventional OFD surgery was applied to patients in all groups which began with local anesthesia (4% articaine with 1:100 000 epinephrine) after the surgical area was disinfected. Defects were thoroughly debrided firstly by using periodontal curettes and then cleaned by piezoelectric ultrasonic scaler. For the control group, the defects were left without adding any products.
Conventional OFD surgery was applied to patients in all groups which began with local anesthesia (4% articaine with 1:100 000 epinephrine) after the surgical area was disinfected. Defects were thoroughly debrided firstly by using periodontal curettes and then cleaned by piezoelectric ultrasonic scaler. After the operation area was washed thoroughly with saline, platelet-rich fibrine (PRF) was placed inside defects
Conventional OFD surgery was applied to patients in all groups which began with local anesthesia (4% articaine with 1:100 000 epinephrine) after the surgical area was disinfected. Defects were thoroughly debrided firstly by using periodontal curettes and then cleaned by piezoelectric ultrasonic scaler. After the operation area was washed thoroughly with saline, Consantrated Growth Factor (CGF) was placed inside defects
Conventional OFD surgery was applied to patients in all groups which began with local anesthesia (4% articaine with 1:100 000 epinephrine) after the surgical area was disinfected. Defects were thoroughly debrided firstly by using periodontal curettes and then cleaned by piezoelectric ultrasonic scaler. After the operation area was washed thoroughly with saline, autologous bone graft (ABG) was placed inside defects