Development of a Novel Anti-caries Chewing Gum
Dental Plaque, Dental Caries, Periodontal Disease
About this trial
This is an interventional prevention trial for Dental Plaque
Eligibility Criteria
Inclusion Criteria: In good general health, no relevant medical history No dental treatment in the previous 3 months Willing to participate and give written informed consent Exclusion Criteria: Patients undergoing fixed or removable orthodontic treatment Patients using removable prosthesis History of head and neck radiation therapy History of adverse reaction or allergies to xylitol or other additives Antibiotics use in the last four weeks Patients with any systemic diseases Xerostomia (also medication-induced) Smokers Currently using any mouth rinse Pregnant or breastfeeding women
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Experimental gum formulation
Placebo
Participants will be asked to chew 2 pieces of chewing gum containing additives 2 times a day for a four-week period
Participants will be asked to chew 2 pieces of pure gum base with no additives chewing gum 2 times a day for the same four-week period.