Harnessing Human Potential and Improving Health Span in Women and Their Children: a Randomized Controlled Trial (HAPPY)
Type 2 Diabetes
About this trial
This is an interventional prevention trial for Type 2 Diabetes focused on measuring Type 2 Diabetes, Gestational Diabetes Mellitus, Women, Prevention, Healthy lifestyle, Physical activity, Diet, Sleep, Mental wellbeing, Digital health interventions
Eligibility Criteria
Inclusion Criteria: Female, age: 21 - 45 years Had a history of GDM (at least 1 year and not more than 10 years) Chinese, Malay or Indian ethnic groups Body mass index (at least 18.5 kg/m2 and not more than 35 kg/m2) Not planning to conceive in the next one year Not performing exclusive breastfeeding during study period Own a smartphone compatible with the study mobile Apps Proficient in English language Plan to stay in Singapore for the next 4 years Willing to comply to study protocol Able to provide a written informed consent Exclusion Criteria: Current or previous diagnosis of diabetes (Type 1 or 2), except GDM Currently pregnant Given birth within the last 12 weeks Severely limited mobility (e.g., wheelchair bound, require long-term walking aid, etc.) Diagnosed with malnutrition or eating disorder Diagnosed with cancers, unstable heart diseases, severe kidney diseases, severe liver diseases Diagnosed with severe insomnia, unstable mental conditions, dementia, or cognitive impairment Experienced alcohol or drug abuse Currently having medications known to influence glucose metabolism (e.g. peroral corticosteroids) Currently participating in concurrent clinical trial or lifestyle intervention study
Sites / Locations
- Singapore Institute for Clinical Sciences (SICS)
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Intervention group
Control group
LvL UP App (Smarphone-based conversational agent-delivered holistic lifestyle intervention for the prevention of type 2 diabetes, and common mental disorders [anxiety, depression]). HAPPY App (Health promotion information, and display health data collected) Oura ring and Oura App (activity-tracking wearable that collects lifestyle data [physical activity, sleep and heart rate]).
HAPPY App (Health promotion information, and display health data collected) Oura ring and Oura App (activity-tracking wearable that collects lifestyle data [physical activity, sleep and heart rate]).