Chemotherapy in the Context of Esophageal and Gastroesophageal Junction Cancer Cachexia (CHIFMEOE)
Esophageal Adenocarcinoma
About this trial
This is an interventional health services research trial for Esophageal Adenocarcinoma focused on measuring Mitochondria, Oxygraphy, Adipose Tissue, Gastroesophageal adenocarcinoma, Energy expenditure
Eligibility Criteria
Inclusion Criteria: Male Patients Patients aged over 18 Patients eligible for neoadjuvant FLOT chemotherapy (5-fluorouracil, oxaliplatin, docetaxel); Patients with a resealable adenocarcinoma of esophageal or gastroesophageal Patients able to give informed consent. Patients affiliated to a Health Care insurance Exclusion Criteria: Unresectable or metastatic esophageal or gastroesophageal adenocarcinoma; Another tumor histology than adenocarcinoma. Patients not eligible for neoadjuvant FLOT chemotherapy and/or for surgery Patients under guardianship, curators or deprived of liberty; Refusal to participate; Patients already participating in another interventional study of pharmacological, nutritional and/or rehabilitation study; Patients in a period of exclusion from another research protocol.
Sites / Locations
- CHU de Clermont-Ferrand
Arms of the Study
Arm 1
Experimental
Interventional
patients with esophageal or gastroesophageal adenocarcinoma included to evaluate the energy expenditure before and after chemotherapy and evaluate parameters of cachexia