Cortical Excitability Modulation With ctDCS in Fibromyalgia. (ctDCS)
Fibromyalgia, Chronic Pain
About this trial
This is an interventional treatment trial for Fibromyalgia focused on measuring Fibromyalgia, Cerebellum, Transcranial direct current magnetic stimulation, Transcranial magnetic stimulation
Eligibility Criteria
Inclusion Criteria: Right-handed women aged 18 to 65 years; who can read and write Confirmed diagnosis of fibromyalgia according to the criteria of the American College of Rheumatology (2010-2016). Pain score equal to or greater than 6 on the Numerical Pain Scale (Score 0-10) on most days in the last 3 months. Exclusion Criteria: Reside outside Porto Alegre area. Confirmed pregnancy Contraindications to TMS and tDCS: metallic implant in the brain; medical devices implanted in the brain, heart pacemaker; cochlear implant; history of alcohol or drug abuse in the last 6 months; neurological pathologies; hx of head trauma or neurosurgery; decompensated systemic diseases and chronic inflammatory diseases (lupus, rheumatoid arthritis, Reiter's syndrome); uncompensated hypothyroidism; personal history of cancer, past or undergoing treatment. Participants with diagnosis or recent contact with COVID will be excluded.
Sites / Locations
- Hospital de Clinicas de Porto AlegreRecruiting
- Hospital de clinicas de Porto AlegreRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Active Comparator
Active Comparator
Active Comparator
Sham Comparator
Active cerebellum electrode and active M1 electrode
Sham cerebellar electrode and active M1 electrode
Active cerebellum electrode and sham M1 electrode
Sham cerebellar electrode and sham M1 electrode
Two tDCS devices will be used simultaneously. In cerebellar stimulation (active), the anodal electrode will be positioned on the right side, with the center of the sponge approximately 3 cm from the ion; on the other hand, in cortical stimulation (active), the anodal electrode will be located in the left primary motor cortex. In both cerebellar and cortical stimulations, the cathode will be positioned in the contralateral supraorbital region. The equipment will apply a current of 2 mA for 20 minutes.
Two tDCS devices will be used simultaneously. In cerebellar stimulation (sham), the anodal electrode will be positioned on the right side, with the center of the sponge approximately 3 cm from the ion; on the other hand, in cortical stimulation (active), the anodal electrode will be located in the left primary motor cortex. In both cerebellar and cortical stimulations, the cathode will be positioned in the contralateral supraorbital region. The equipment will apply a current of 2 mA for 20 minutes.
Two tDCS devices will be used simultaneously. In cerebellar stimulation (active), the anodal electrode will be positioned on the right side, with the center of the sponge approximately 3 cm from the ion; on the other hand, in cortical stimulation (sham), the anodal electrode will be located in the left primary motor cortex. In both cerebellar and cortical stimulations, the cathode will be positioned in the contralateral supraorbital region. The equipment will apply a current of 2 mA for 20 minutes
Two tDCS devices will be used simultaneously. In cerebellar stimulation (sham), the anodal electrode will be positioned on the right side, with the center of the sponge approximately 3 cm from the ion; on the other hand, in cortical stimulation (sham), the anodal electrode will be located in the left primary motor cortex. In both cerebellar and cortical stimulations, the cathode will be positioned in the contralateral supraorbital region. The equipment will apply a current of 2 mA for 20 minutes