Peri-implantitis and Systemic Inflammation (LASSO)
Peri-Implantitis and Systemic Inflammation
About this trial
This is an interventional treatment trial for Peri-Implantitis and Systemic Inflammation
Eligibility Criteria
Inclusion Criteria: At least 18 years of age and in good general health A minimum of 20 teeth Participants must have at least one implant in situ with peri-implantitis as per its case definition Must voluntarily agree to sign the consent form Exclusion Criteria: Currently on any weight reduction program History of diabetes Uncontrolled or currently undergoing treatment for systemic medical conditions Chronic treatment (defined as 2 weeks or more) of antibiotic, anti-inflammatory or anticoagulant therapy during the month preceding the baseline assessment Taking statins drugs History of alcohol or drug abuse Self-reported pregnancy or breastfeeding Patients who have active periodontitis as per its case definition and/or have had treatment for periodontitis within the last 1 year
Sites / Locations
- University College LondonRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Active Comparator
Group A - Non-surgical hand instruments
Group B - Non-surgical Air-flow
Group C - Surgical Air-flow
After appropriate local anaesthesia of the treatment site supragingival, subgingival and implant surface debridement will be undertaken with Hu-Friedy titanium implant hand instruments only. Any remaining supragingival deposits will be polished using a contra-angle handpiece, rubber cup and Cleanic polishing paste.
After appropriate local anaesthesia of the treatment site supragingival, subgingival and implant surface debridement will be undertaken using EMS PerioFlow with Plus powder (Erythritol) and supplemented with EMS Piezon and EMS AirFlow and Plus powder as required.
After appropriate local anaesthesia of the treatment site a full thickness mucoperiosteal flap will be raised to adequately expose the tissue defect. Supragingival, subgingival and implant surface debridement will be undertaken using EMS PerioFlow with Plus powder (Erythritol) and supplemented with EMS Piezon and EMS AirFlow and Plus powder as required.