Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars
Molar Incisor Hypomineralization, Anesthesia, Local
About this trial
This is an interventional treatment trial for Molar Incisor Hypomineralization focused on measuring Silver diamine fluoride
Eligibility Criteria
Inclusion Criteria: At least one hypomineralized first permanent molar with a primary cavitated caries lesion(s) or a cavitated tooth defect requiring restorative dental care with local anesthesia American Society of Anesthesiologists (ASA) Physical Status Classification I or II (healthy children or those with mild systemic disease) English speaking Subjects for which basic behavior guidance (non-pharmacological or nitrous oxide/oxygen) is indicated Exclusion Criteria: Teeth with irreversible pulpitis and pulp necrosis Patients requiring advanced behavior management such as moderate sedation, general anesthesia, and/or active or passive restraint Inability of the child to cooperate due to special needs or other conditions Allergy to SDF, local anesthetic or other material component Subjects with ulcerative gingivitis or stomatitis Subjects with known sensitivity to silver or other heavy-metal ions Subjects showing abnormal skin sensitization in daily circumstances
Sites / Locations
- University of MichiganRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
SDF
Placebo
38% SDF applied to hypomineralized permanent molar two weeks prior to restorative care of the tooth.
Inert liquid (colored water) applied to hypomineralized permanent molar two weeks prior to restorative care of the tooth.