The Study on Effect and Neural Network Mechanism of Transcranial Direct Current Stimulation for Sudden Deafness With Tinnitus
Tinnitus, Subjective, Sudden Deafness, Transcranial Direct Current Stimulation
About this trial
This is an interventional treatment trial for Tinnitus, Subjective focused on measuring Acute subjective tinnitus, Clinical trial, Transcranial Direct Current Stimulation
Eligibility Criteria
Inclusion Criteria: Patients with tinnitus as the main complaint: patients subjectively feel sound in the ear or deep part of the head without internal or external sound stimulation, with or without hearing loss, and seek medical treatment Patients with sudden deafness with tinnitus whose course is less than 1 month and have not received any drug treatment Age 18-60 years Tinnitus frequency is 125-8000 Hz Exclusion Criteria: Patients with conductive deafness, history of middle ear surgery, pulsatile tinnitus caused by vascular aberration and tinnitus cause by Meniere disease History of head trauma, central nervous system disease, mental disease, and drug abuse
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Sham Comparator
Receive traditional medical therapy and transcranial direct current stimulation
Receive traditional medical therapy and sham stimulation
intravenous methylprednisolone infusion (dose of 1 mg/kg/day, maximum 60 mg/day) for 5 to 10 days. Patients included in this study were routinely examined and tested for audiometry, including otoscopy, pure tone audiometry, acoustic impedance, brainstem evoked potential, and tinnitus detection. After completion, the 32-guide EEG collector from Bricon was used to collect changes in neural activity in all subjects.
Similarly, intravenous methylprednisolone infusion (dose of 1 mg/kg/day, maximum 60 mg/day) for 5 to 10 days. By controlling the tDCS stimulator to mimic only the first 30 seconds of tDCS stimulation, after 30 seconds of pathway resistance control, so that the stimulation intensity is below the threshold, without giving real stimulation, in this process, the position of the stimulation target is not changed, and the rest of the operation is the same.