Effects of Continuous Positive Airway Pressure on Peripheral Oxygen Saturation, Work of Breathing, and Exercise Tolerance at Altitude
Hypoxemia, Altitude Hypoxia
About this trial
This is an interventional other trial for Hypoxemia
Eligibility Criteria
Inclusion Criteria: Healthy adults (age 18-70) Living at lower elevation (<2500m or 8200ft) Exclusion Criteria: Age > 70 or age < 18. History of chronic respiratory conditions (asthma, COPD, ILD) Obstructive sleep apnea (if currently using nighttime CPAP) Congestive heart failure, coronary artery disease History of myocardial infarction History of HAPE Neurologic disorder Cognitive disorder Altered mental status Pregnancy Current use of supplemental oxygen Impaired mobility Excessive facial hair Claustrophobia. Current use of altitude-related illness prophylaxis medications Current use of anticoagulant medications Current use of calcium channel blockers medications
Sites / Locations
- University of Colorado Denver
Arms of the Study
Arm 1
Arm 2
Experimental
Sham Comparator
Continuous Positive Airway Pressure use
Ambient air