Chronic Hypertension and Pregnancy 2 (CHAP2) Pilot Project (CHAP2)
Hypertension in Pregnancy
About this trial
This is an interventional treatment trial for Hypertension in Pregnancy
Eligibility Criteria
Inclusion Criteria: Viable singleton gestation No fetal anomalies Blood pressures 130-139/80-89mmHg on two occasions at least 4 hours apart prior to 20 weeks gestation Planning to deliver at UAB Hospital No indication for pregnancy termination Receiving care at the UAB prenatal clinics Exclusion Criteria: Declines Randomization Known diagnosis of chronic hypertension ( BP ≥ 140/90mmHg) or current antihypertensive medication use Fetal demise diagnosed prior to enrollment Known major structural of chromosomal abnormalities prior to enrollment Contraindication to first line antihypertensive (Nifedipine/ Labetalol) Comorbidities requiring BP goals < 130/80mmHg
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
BP goal <130/80mmHg
BP goal <140/90 (usual care)