Injection of Botulinum Toxin for Thumb Carpometacarpal Arthritis
Carpometacarpal Sprain, Thumb Sprain, Clostridium; Botulinum
About this trial
This is an interventional treatment trial for Carpometacarpal Sprain focused on measuring Botulinum toxin, Carpometacarpal joint arthritis
Eligibility Criteria
Inclusion Criteria: Adult patients (> 18 years old) with a diagnosis of thumb CMC OA Diagnosis of thumb CMC OA History, clinical exam, and radiographic findings, as done in prior studies on this topic. Subjective: thumb or wrist pain at rest or with activity, joint stiffness Exam: basal joint tenderness, decreased mobility, deformity, instability Radiograph: joint space narrowing, subchondral sclerosis, osteophytes, subchondral cysts, Eaton-Littler stage. Failed conservative management with oral pain medication and splinting for at least 3 months. Exclusion Criteria: Severe osteoarthritis (Eaton-Littler stage 4) or too large osteophytes to allow for injection into the joint space Inflammatory arthritis Any concomitant hand conditions (i.e. carpal tunnel, trigger finger, etc) Prior significant hand trauma related to the thumb or first CMC joint Prior intervention or hand surgery Patients with fibromyalgia or complex regional pain syndrome (CRPS) Pregnant and breastfeeding patients will also be excluded. We also will exclude individuals attempting to conceive or who could become pregnant within 6-months of treatment.
Sites / Locations
- 235 Plain StreetRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Control
Botulinum Toxin
Patients in this group will receive standard-of-care corticosteroid injections.
Patients in this group will receive a Botulinum Toxin injection.