Pain Treatment With Combinations of NSAIDs
Postoperative Pain, Acute
About this trial
This is an interventional treatment trial for Postoperative Pain, Acute focused on measuring Postoperative pain, Non-steroidal anti-inflammatory drugs, Combination of NSAID, Aspirin, Ketorolac, Celecoxib
Eligibility Criteria
Inclusion Criteria: The patients with diagnosis of osteoarthritis of the knee or hip joint (M15.0, M16, M17) after primary knee or hip arthroplasty. Exclusion Criteria: Pregnant or breast feeding women, opioid addiction, patients with severe kidney or liver disease
Sites / Locations
- Federal Center for Traumatology, Orthopedics and Endoprosthetics
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Active Comparator
Experimental
Experimental
Active Comparator
Drug: celecoxib
Drug: aspirin with ketorolac
Drug: ketorolac and celecoxib
Drug: aspirin, ketorolac and celecoxib
The patients received celecoxib in a dose of 400 mg orally daily. The drug was prescribed from the second day of the operation for 5 days.
The patients received aspirin in a dose of 100 mg and ketorolac 90 mg orally daily. The drugs were prescribed from the second day of the operation for 5 days.
The patients received ketorolac in a dose of 90 mg and celecoxib 400 mg orally daily. The drugs were prescribed from the second day of the operation for 5 days.
The patients received aspirin in a dose of 200 mg, ketorolac 90 mg, and celecoxib 400 mg orally daily. The drugs were prescribed from the second day of the operation for 5 days.