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Retrieval-Based Word Learning in Developmental Language Disorder: Verb Learning

Primary Purpose

Developmental Language Disorder, Specific Language Impairment, Language Development

Status
Recruiting
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Retrieval-based verb learning
Sponsored by
Purdue University
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional basic science trial for Developmental Language Disorder focused on measuring word learning, word retrieval, preschool-aged children

Eligibility Criteria

48 Months - 71 Months (Child)All SexesAccepts Healthy Volunteers

Inclusion Criteria: a significant deficit in language ability (language test score below cutoff for best sensitivity/specificity) or documented age-appropriate language ability. normal hearing no evidence of neurological damage or disease scores on tests of nonverbal intelligence above the intellectual disability range not within Autistic range on Autism screening test native English speaker (can be bilingual) Exclusion Criteria: failed hearing screening known neurological damage or disease scores on tests of nonverbal intelligence below the intellectual disability range (standard score less than 75) autism spectrum disorder non-native English speaker

Sites / Locations

  • Purdue UniversityRecruiting

Arms of the Study

Arm 1

Arm Type

Experimental

Arm Label

Spaced Retrieval practice during verb learning

Arm Description

Each child will learn 8 novel verbs referring to unfamiliar transitive actions ("mape"). Four verbs will be learned in a condition requiring spaced retrieval practice; four verbs will be learned in a "standard" study-only (no retrieval practice) condition. In the spaced retrieval condition, the number of other words intervening between hearing the target and an attempt to retrieve it will increase from 0 to 3 words. In the study-only condition, children will simply hear the verb used to describe the action.

Outcomes

Primary Outcome Measures

Word form recall accuracy (number of verbs correctly recalled)
Child is asked to recall and use the verb associated with each novel action in a sentence (X is VERBing the Y).
Word form recall accuracy (number of verbs correctly recalled)
Child is asked to recall and use the verb associated with each novel action in a sentence (X is VERBing the Y).
Accuracy of generalizing novel verb to a new syntactic frame (number of verbs used in a syntactic frame different from the one used in initial learning and recall).
Child is asked to describe the video of a novel action using the frame "X likes to VERB the Y."
Word recognition (number of words accurately identified)
Upon hearing a novel word, the child is asked to indicate (by pointing) which video among 2 options is referred to.

Secondary Outcome Measures

Number of correctly identified words on Peabody Picture Vocabulary Test, 5th Ed.
Upon hearing a word, the child is asked to indicate (by pointing) which picture among 4 options is referred to.
Years of maternal education
Primary care-giver provides information regarding highest academic degree attained, converted to years of education

Full Information

First Posted
August 3, 2023
Last Updated
August 16, 2023
Sponsor
Purdue University
Collaborators
National Institute on Deafness and Other Communication Disorders (NIDCD)
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1. Study Identification

Unique Protocol Identification Number
NCT06001866
Brief Title
Retrieval-Based Word Learning in Developmental Language Disorder: Verb Learning
Official Title
Retrieval-Based Word Learning in Developmental Language Disorder: Verb Learning
Study Type
Interventional

2. Study Status

Record Verification Date
August 2023
Overall Recruitment Status
Recruiting
Study Start Date
March 1, 2023 (Actual)
Primary Completion Date
July 31, 2026 (Anticipated)
Study Completion Date
July 31, 2026 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Purdue University
Collaborators
National Institute on Deafness and Other Communication Disorders (NIDCD)

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No

5. Study Description

Brief Summary
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and eventual economic wellbeing. Word learning is one of the principal weaknesses in these children. This project focuses on the word learning abilities of four- and five-year-old children with DLD. The goal of the project is to build on the investigators' previous work to determine whether, as has been found thus far, special benefits accrue when these children must frequently recall newly introduced words during the course of learning. The focus of the current study is verb-learning. The goal of the study is to increase children's absolute levels of learning while maintaining the advantage that repeated retrieval holds over comparison methods of learning.
Detailed Description
Developmental Language Disorder (DLD) affects language learning in an estimated 7% of children. Although much of the research literature has emphasized difficulties learning grammar, children with DLD also have major deficits in vocabulary. In recent work, the investigators have been examining the benefit of retrieval practice to enhance word learning and retention in preschoolers with DLD. The rationale behind this work is grounded in the growing literature in the field of cognitive psychology which shows that repeated practice in retrieving information results in greater long-term retention than continuous study of that information without opportunities for retrieval. In addition, retrieval practice that occurs after a delay-or "spacing" between study of a word and subsequent recall attempts-can lead to stronger effects. The investigators have explored the benefits of retrieval practice for preschoolers with DLD and with typical language development (TD), showing that recall and retention for novel words (nouns, adjectives, verbs) were greater when learned using repeated spaced retrieval (RSR) than when learned using repeated study only. Despite benefitting from RSR, children with DLD still showed lower levels of recall than children with TD, in particular in novel verb learning. In the current study, the investigators seek to improve the absolute levels of word form recall for verbs by modifying the method used previously. Sixteen children with DLD will be recruited for this study along with 16 children with TD matched on chronological age. Using a within-subjects design, children will learn eight novel verbs, four at a time. Each set of four will be learned over two consecutive days, with two words in the RSR condition and two words in a repeated study condition. The referents for these novel words will be video-recorded transitive actions performed by actors on objects and presented on a laptop screen. In the RSR condition, children will initially hear the word paired with a video of a novel action, immediately be asked to recall the word, and then see/hear it again. After three other words are presented, they will be asked to recall the original word again; this "3" spaced retrieval schedule will continue for the rest of the learning session. In the comparison condition, children will simply hear the words paired with a video of the novel action. In this study, during retrieval practice, children will be prompted to respond with a full sentence containing the verb. Recall of the verbs will be tested after the learning session on the second day and one week later. At one week, children will also complete a syntactic generalization test in which they are prompted to use the novel verb in a type of sentence that is different from the one used during learning. Finally, children will complete a two-alternative recognition test. The investigators hypothesize that novel verbs that undergo RSR during the learning period will be learned and recalled better than comparable novel verbs that are assigned to the repeated study condition. This RSR advantage will continue to be observed when the children must use the novel verbs with new actors and objects and will be seen as well in the syntactic generalization test when the children must use the novel verbs in a new sentence frame. Introducing novel verbs representing actions that can be performed on varying objects is expected to improve overall learning. In addition, by having the child produce the verbs in the context of a full sentence, the newly learned verbs should become more integrated with other sentence elements (subjects and direct objects), resulting in a richer representation in memory and consequently, greater recall, recognition, and syntactic flexibility than was observed in the previous novel verb study.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Developmental Language Disorder, Specific Language Impairment, Language Development
Keywords
word learning, word retrieval, preschool-aged children

7. Study Design

Primary Purpose
Basic Science
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Model Description
Within-participant design in which each child learns words under two conditions.
Masking
None (Open Label)
Allocation
N/A
Enrollment
32 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Spaced Retrieval practice during verb learning
Arm Type
Experimental
Arm Description
Each child will learn 8 novel verbs referring to unfamiliar transitive actions ("mape"). Four verbs will be learned in a condition requiring spaced retrieval practice; four verbs will be learned in a "standard" study-only (no retrieval practice) condition. In the spaced retrieval condition, the number of other words intervening between hearing the target and an attempt to retrieve it will increase from 0 to 3 words. In the study-only condition, children will simply hear the verb used to describe the action.
Intervention Type
Behavioral
Intervention Name(s)
Retrieval-based verb learning
Intervention Description
Learning sessions: Novel verbs are practiced on Day 1. In one condition, the words are learned using repeated spaced retrieval practice - retrieval trials are initially immediate, then occur after 3 intervening words. In the other condition, the words and video are presented without retrieval trials. This practice schedule is repeated the next day (Day 2). Testing sessions: 5 minutes after the learning session on Day 2, the child is asked to recall each word in the context of a sentence twice with actors and objects viewed during learning and twice with new actors and objects. One week after Day 1, this recall test is completed again. At this time, the child's ability to generalize the verb to a new sentence frame will be assessed. Finally, the child will complete a recognition test: viewing pairs of video clips, the child will hear each novel verb and point to the video clip that depicts that action.
Primary Outcome Measure Information:
Title
Word form recall accuracy (number of verbs correctly recalled)
Description
Child is asked to recall and use the verb associated with each novel action in a sentence (X is VERBing the Y).
Time Frame
5 minutes after end of learning period
Title
Word form recall accuracy (number of verbs correctly recalled)
Description
Child is asked to recall and use the verb associated with each novel action in a sentence (X is VERBing the Y).
Time Frame
1 week after end of learning period
Title
Accuracy of generalizing novel verb to a new syntactic frame (number of verbs used in a syntactic frame different from the one used in initial learning and recall).
Description
Child is asked to describe the video of a novel action using the frame "X likes to VERB the Y."
Time Frame
1 week after end of learning period
Title
Word recognition (number of words accurately identified)
Description
Upon hearing a novel word, the child is asked to indicate (by pointing) which video among 2 options is referred to.
Time Frame
1 week after end of learning period
Secondary Outcome Measure Information:
Title
Number of correctly identified words on Peabody Picture Vocabulary Test, 5th Ed.
Description
Upon hearing a word, the child is asked to indicate (by pointing) which picture among 4 options is referred to.
Time Frame
completed at start of study
Title
Years of maternal education
Description
Primary care-giver provides information regarding highest academic degree attained, converted to years of education
Time Frame
information collected at start of study

10. Eligibility

Sex
All
Minimum Age & Unit of Time
48 Months
Maximum Age & Unit of Time
71 Months
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: a significant deficit in language ability (language test score below cutoff for best sensitivity/specificity) or documented age-appropriate language ability. normal hearing no evidence of neurological damage or disease scores on tests of nonverbal intelligence above the intellectual disability range not within Autistic range on Autism screening test native English speaker (can be bilingual) Exclusion Criteria: failed hearing screening known neurological damage or disease scores on tests of nonverbal intelligence below the intellectual disability range (standard score less than 75) autism spectrum disorder non-native English speaker
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Patricia L. Deevy, PhD
Phone
765-496-1821
Email
deevy@purdue.edu
First Name & Middle Initial & Last Name or Official Title & Degree
Laurence B. Leonard, PhD
Phone
765-496-2253
Email
xdxl@purdue.edu
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Laurence B. Leonard, PhD
Organizational Affiliation
Purdue Universtiy
Official's Role
Principal Investigator
Facility Information:
Facility Name
Purdue University
City
West Lafayette
State/Province
Indiana
ZIP/Postal Code
47907
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Patricia L Deevy, PhD
Phone
765-496-1821
Email
deevy@purdue.edu
First Name & Middle Initial & Last Name & Degree
Laurence B Leonard, PhD
Phone
765-496-2253
Email
xdxl@purdue.edu

12. IPD Sharing Statement

Plan to Share IPD
Yes
IPD Sharing Plan Description
Data that contribute to our final published results will be made available at www.clinicaltrials.gov.
IPD Sharing Time Frame
Data will become available after the results are published or within 12 months from the primary completion date (i.e., the date of final data collection for the primary outcome measure).
IPD Sharing Access Criteria
De-identified data will be made publicly available at www.clinicaltrials.gov

Learn more about this trial

Retrieval-Based Word Learning in Developmental Language Disorder: Verb Learning

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