OPT-IN: Online Parent Training Intervention for Young Children Diagnosed With Autism Spectrum Disorder
Primary Purpose
Autism Spectrum Disorder
Status
Not yet recruiting
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
OPT-IN
Psychoeducational control
Sponsored by
About this trial
This is an interventional treatment trial for Autism Spectrum Disorder
Eligibility Criteria
Inclusion Criteria: Child diagnosed with Autism or Autism Spectrum Disorder within the last six months at baseline Exclusion Criteria: Parent does not speak English well enough to complete questionnaires Parent or child has complete vision or hearing loss. Parent or child is medically unstable.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
Active Comparator
Arm Label
OPT-IN intervention
Psychoeducational control
Arm Description
Outcomes
Primary Outcome Measures
Change in Adaptive Behavior
Change in Vineland Adaptive Behavior Scales, 3rd Edition Parent interview
Secondary Outcome Measures
Change in Autism Symptoms
Change in Autism Impact Measure
Change in Parenting Stress
Change in Parenting Stress Index, Short Form, version 4
Change in Parental Self-Efficacy
Change in Early Intervention Parenting Self-Efficacy Scale
Change in Language
Change in MacArthur-Bates Communicative Development Inventory
Full Information
NCT ID
NCT06011707
First Posted
April 24, 2023
Last Updated
August 23, 2023
Sponsor
Elizabeth Kelley
Collaborators
McMaster Children's Hospital, Holland Bloorview Kids Rehabilitation Hospital, Children's Hospital of Eastern Ontario, Child and Community Resources
1. Study Identification
Unique Protocol Identification Number
NCT06011707
Brief Title
OPT-IN: Online Parent Training Intervention for Young Children Diagnosed With Autism Spectrum Disorder
Official Title
OPT-IN: Online Parent Training Intervention for Young Children Diagnosed With Autism Spectrum Disorder: A Randomized Controlled Trial
Study Type
Interventional
2. Study Status
Record Verification Date
August 2023
Overall Recruitment Status
Not yet recruiting
Study Start Date
November 1, 2023 (Anticipated)
Primary Completion Date
March 2028 (Anticipated)
Study Completion Date
March 2028 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor-Investigator
Name of the Sponsor
Elizabeth Kelley
Collaborators
McMaster Children's Hospital, Holland Bloorview Kids Rehabilitation Hospital, Children's Hospital of Eastern Ontario, Child and Community Resources
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
The goal of this observer-blinded randomized controlled clinical trial is to determine the effectiveness of a fully-online, parent-mediated, video-based, self-directed intervention for young children with autism (12-60 months) who have been diagnosed with autism in the last six months. The main question[s] it aims to answer are:
Does an online intervention for autistic children result in improved adaptive behaviour, compared to a psychoeducational control group?
Does an online intervention for autistic children result in reduced autism symptoms in children, and decreased stress and increased self-efficacy in parents, compared to a psychoeducational control group?
What are the predictors of response to intervention (i.e., child sex and age; initial autism symptoms and adaptive behavior; and parent self-efficacy, stress, and education).
Parents will be given six compulsory and eight optional online modules that will teach them skills to use while interacting with their autistic children to improve social and communication behaviours and minimize behaviours that interfere with learning.
The comparison group will receive six compulsory and eight optional online modules that will teach them about autism more broadly including diagnostic criteria, symptom profiles across development, etc.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Autism Spectrum Disorder
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
Investigator
Masking Description
The students who will be conducting the interviews for the primary objective of the study (using the Vineland Adaptive Behavior Scales, Version 3) will be blind to the treatment arm the family is assigned to.
Allocation
Randomized
Enrollment
308 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
OPT-IN intervention
Arm Type
Experimental
Arm Title
Psychoeducational control
Arm Type
Active Comparator
Intervention Type
Behavioral
Intervention Name(s)
OPT-IN
Intervention Description
Parents will be provided with online access to 6 compulsory video-based modules and 8 optional video-based modules. These modules will teach them about child development, behavioural principles, and naturalistic developmental intervention principles. These modules will promote skills that parents can use to increase their child's social and communication behaviours and minimize behaviours that interfere with learning (e.g., temper tantrums).
Intervention Type
Other
Intervention Name(s)
Psychoeducational control
Intervention Description
This control intervention will provide parents with 6 compulsory and 8 optional modules that will teach them about autism and its developmental course.
Primary Outcome Measure Information:
Title
Change in Adaptive Behavior
Description
Change in Vineland Adaptive Behavior Scales, 3rd Edition Parent interview
Time Frame
baseline, post-intervention (6 months past baseline), follow-up (6 months past post-intervention)
Secondary Outcome Measure Information:
Title
Change in Autism Symptoms
Description
Change in Autism Impact Measure
Time Frame
baseline, post-intervention (6 months past baseline), follow-up (6 months past post-intervention)
Title
Change in Parenting Stress
Description
Change in Parenting Stress Index, Short Form, version 4
Time Frame
baseline, post-intervention (6 months past baseline), follow-up (6 months past post-intervention)
Title
Change in Parental Self-Efficacy
Description
Change in Early Intervention Parenting Self-Efficacy Scale
Time Frame
baseline, post-intervention (6 months past baseline), follow-up (6 months past post-intervention)
Title
Change in Language
Description
Change in MacArthur-Bates Communicative Development Inventory
Time Frame
baseline, post-intervention (6 months past baseline), follow-up (6 months past post-intervention)
10. Eligibility
Sex
All
Minimum Age & Unit of Time
12 Months
Maximum Age & Unit of Time
60 Months
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Child diagnosed with Autism or Autism Spectrum Disorder within the last six months at baseline
Exclusion Criteria:
Parent does not speak English well enough to complete questionnaires
Parent or child has complete vision or hearing loss.
Parent or child is medically unstable.
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Elizabeth A Kelley, PhD
Phone
613-533-2491
Email
kelleyb@queensu.ca
12. IPD Sharing Statement
Plan to Share IPD
Yes
IPD Sharing Plan Description
Data will be shared with other researchers through this website. The data will be de-identified by eliminating birthdate.
IPD Sharing Time Frame
The data will be made available after publication for 15 years.
IPD Sharing Access Criteria
Data will be obtained through the clinicaltrials.gov website
Learn more about this trial
OPT-IN: Online Parent Training Intervention for Young Children Diagnosed With Autism Spectrum Disorder
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