Transcutaneous Electrical Stimulation for Spasticity in Patients With Primary Lateral Sclerosis
Primary Lateral Sclerosis
About this trial
This is an interventional treatment trial for Primary Lateral Sclerosis
Eligibility Criteria
Inclusion Criteria: Diagnosis of primary lateral sclerosis by the treating neurologist Ambulatory with or without a assistive device or orthotic Exclusion Criteria: History of cancer in the lumbar or thoracic spine History of surgery with hardware in the lumbar or thoracic spine Acute lower back pathology Current pregnancy History of implantable cardiac device Diagnosis of significant cognitive impairment by the treating physician History of seizures or diagnosis of epilepsy Open wound at location of electrodes Complete loss of sensation at the area of electrode placement
Sites / Locations
- NSU Health Neuroscience InstituteRecruiting
Arms of the Study
Arm 1
Experimental
Transcutaneous electrical stimulation to reduce spasticity in PLS
Primary lateral sclerosis (PLS) is a progressive upper motor neuron neurodegenerative disorder. A hallmark of PLS is a presentation with lower extremity stiffness and spasticity as well as bulbar involvement. The investigators will be performing a preliminary study designed to assess transcutaneous electrical stimulation (tES), a non-pharmacological and non-invasive modality used in spinal cord injury and multiple sclerosis patients, as a treatment for reducing spasticity in the lower extremities and increasing mobility in patients with PLS.