Interventional X-ray and Scintigraphy Imaging of 99mTc-MAA During the Radioembolisation Pretreatment Procedure (IXSI)
Liver Cancer
About this trial
This is an interventional device feasibility trial for Liver Cancer
Eligibility Criteria
Inclusion Criteria: Participants must have given written informed consent and comply with the requirements of the study protocol. Must be aged 18 years or over. Must be selected to undergo a 99mTc-MAA procedure as part of their radioembolisation treatment. Sufficiently fit to undergo an additional examination time of 30-90 minutes. Have a CT acquired less than 6 weeks before the pre-treatment radioembolisation procedure. Exclusion Criteria: Patients expected to require more than two injection positions for radioembolisation treatment. Pregnancy or nursing. Patients suffering from psychic disorders that make a comprehensive judgement impossible, such as psychosis, hallucinations and/or depression. Patients who are declared incompetent. Previous enrollment in the present study Claustrophobia The last dose of prior chemotherapy has been received less than weeks prior to the planned 99mTc-MAA pre-treatment procedure. Radiation therapy within the last 4 weeks before the planned 99mTc-MAA pre-treatment procedure Major surgery within the last 4 weeks prior to the planned 99mTc-MAA pre-treatment procedure Any unresolved toxicity greater than Common Terminology Criteria for Adverse Events (CTCAE version 5) grade 2 from previous anti-cancer treatment Body weight over 250 kg (because of maximum table load) Patient length over 1.90 m (to fit IXSI geometry) Patient bust line over 135 cm (to fit IXSI geometry)
Sites / Locations
- UMC Utrecht
Arms of the Study
Arm 1
Experimental
Hybrid imaging during the pre-treatment procedure of radioembolization
Hybrid imaging will be performed on patients undergoing the pre-treatment procedure of radioembolization