Improving Survivorship and Health-related Quality of Life in Patients With Primary Brain Tumours
Hypopituitarism, Radiotherapy-Induced Hypopituitarism, Brain Tumor
About this trial
This is an interventional diagnostic trial for Hypopituitarism
Eligibility Criteria
Inclusion Criteria: Adults (at least 18 years old) with a history of a primary, non-pituitary brain tumour which was previously treated with radiotherapy. Participants must have been at least 16 years old at the time of undergoing radiotherapy. A minimum of one year has elapsed since radiotherapy was completed. Capacity and willingness to provide informed consent. Exclusion Criteria: Diagnosed with malignant astrocytic brain tumour with life expectancy of less than six months. Brain tumour infiltration of the hypothalamus or pituitary pre-operatively. Previously diagnosis of hypopituitarism. Oral glucocorticoid use within the last three months. Pregnant or breastfeeding women at the time of recruitment. Unable to provide informed consent for inclusion in this study. Opinion of the radiation oncology or research team that participation in the study is not in the best interest of the patient for any reason.
Sites / Locations
- Beaumont Hospital
- St Luke's Radiation oncology Centre, Beaumont Hopsital
Arms of the Study
Arm 1
Experimental
Study investigation
All enrolled patients will undergo standardised pituitary hormone assessments.