Alleviating Persistent Dyspnea in Amyotrophic Lateral Sclerosis Patients Treated With Non-Invasive Ventilation Through Immersive Virtual Reality (RVI-SLA)
Amyotrophic Lateral Sclerosis
About this trial
This is an interventional supportive care trial for Amyotrophic Lateral Sclerosis focused on measuring Persistent Dyspnea, Non-Invasive Ventilation, Immersive Virtual Reality
Eligibility Criteria
Inclusion Criteria: ≥ 18 years old Diagnosis of ALS confirmed according to the revised criteria of El Escorial Respiratory failure due to diaphragmatic dysfunction treated by non-invasive ventilation for more than a month Care provided in an ambulatory setting (day care hospital) Persistent dyspnea at rest ≥ 3 across a numerical scale (0 to 10) in a semi-sitting position Stable clinical condition, i.e., no episode of acute cardiac, respiratory and/or neurological failure leading to hospitalization in the previous 4 weeks Free, prior and informed written consent about the study has been obtained Benefiting a social security (French health insurance system) Exclusion Criteria: Neurological disorders according to a neurological evaluation dating from less than one year, in particular diagnosed dementia (frontotemporal dementia, Alzheimer's disease, etc.), brain pathology (tumor, stroke, Parkinson's disease, etc.) Diagnosed psychiatric illness (severe depression, psychosis) or receiving antipsychotic treatment Acrophobia Claustrophobia Photophobia Hearing loss Visual impairment Subject under guardianship or curatorship
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Patients starting with RVI
Patients starting with music therapy
Patients will begin by wear a virtual reality headset (GAMIDA®) and headphones (Bose®). A tablet (Samsung®) equipped with "Healthy Mind" software will allow patients to live a 360° visual and auditory 3D experience via Bluetooth connection. After that patients will be handed a smartphone with the Spotify® application to listen to music. Patients will wear headphones.
Patients will begin by handed a smartphone with the Spotify® application to listen to music. Patients will wear headphones. After that patients will wear a virtual reality headset (GAMIDA®) and headphones (Bose®). A tablet (Samsung®) equipped with "Healthy Mind" software will allow patients to live a 360° visual and auditory 3D experience via Bluetooth connection.