Safely Reduce Cystoscopic Evaluations for Hematuria Patients (SeARCH)
Hematuria, Urothelial Neoplasm, Urothelial Carcinoma
About this trial
This is an interventional diagnostic trial for Hematuria focused on measuring Urinary biomarker, Hematuria, Urothelial Carcinoma, Bladder Cancer
Eligibility Criteria
Inclusion Criteria: Microscopically confirmed microscopic hematuria of voided urine defined as ≥3 erythrocytes per high power field Male patients ≥40 years Female patients ≥50 years Exclusion Criteria: History of urothelial bladder- or urinary tract cancer Presence of macroscopic (visible) hematuria Woman who is or may be pregnant
Sites / Locations
- SeARCH-trial PijpersRecruiting
Arms of the Study
Arm 1
Arm 2
No Intervention
Experimental
Care-as-usual
'Urine-first' strategy
In the ''care-as-usual'' arm, all patients undergo 'care-as-usual', i.e. a cystoscopy and upper tract imaging (ultrasound or CT-scan)
In the intervention arm, the urine test is used to triage patients for a diagnostic workup ('urine-first' strategy). Only patients with an abnormal test result undergo cystoscopy and upper tract imaging.