PRP Injections for Genitourinary Syndrome of Menopause
PRP, Sexual Function Disturbances, Genitourinary Syndrome of Menopause
About this trial
This is an interventional treatment trial for PRP
Eligibility Criteria
Inclusion Criteria: Women (assigned female at birth) at least 18 years old with a clinical diagnosis of GSM Sexually active with at least one episode of sexual activity per week in the preceding 4 weeks defined as follows: Partnered or solo penetrative or non-penetrative stimulation of the clitoris or vagina English-speaking Willingness and able to comply with the study requirements Exclusion Criteria: Symptomatic pelvic organ prolapse protruding beyond the hymen) History of prior vaginal mesh or midurethral mesh sling surgery History of pelvic radiation or genital tract malignancy Current symptomatic pelvic organ prolapse (stage II or greater) Active vulvar dermatoses or genitourinary infection Unable to hold anticoagulation Hormonal replacement therapy (systemic, local, or vaginal) within 3 months of participation Pregnancy or pre-menopausal status
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Sham Comparator
Platelet-rich plasma injection
0.9% saline injection