Stroke and CPAP Outcome Study 3 (SCOUTS3)
Ischemic Stroke, Intra Cerebral Hemorrhage, Obstructive Sleep Apnea
![University of Washington](https://trials-media.s3.amazonaws.com/orgs/university-of-washington.jpeg)
About this trial
This is an interventional treatment trial for Ischemic Stroke focused on measuring behavioral therapy, continuous positive airway pressure, rehabilitation therapy, stroke recovery, self determination
Eligibility Criteria
Inclusion Criteria: Age 18 years or older Head CT or brain MRI demonstrating an acute ischemic infarction or intraparenchymal hemorrhage within past 30 days Person providing consent (patient or legally authorized representative) able to be consented in English or Spanish Exclusion Criteria: Unable to obtain informed consent from participant or surrogate Incarcerated Known pregnancy Current mechanical ventilation, tracheostomy or supplemental oxygen use > 4L/min Current use of positive airway pressure or use within 14 days prior to stroke History of pneumothorax, bullous emphysema or other serious co-morbid conditions which limit CPAP use Stroke related to tumors, vascular malformations or subarachnoid hemorrhage Active use of sedative drugs that can interfere with testing for obstructive sleep apnea (OSA) Anticipated inpatient rehabilitation length of stay < 3 nights
Sites / Locations
- University of WashingtonRecruiting
Arms of the Study
Arm 1
Experimental
SCOUTS3 Optimization Arm
In a single-arm study, participants from acute ischemic stroke or intraparenchymal hemorrhage within the past 30 days will be tested for OSA with a single-night portable OSA test during inpatient rehabilitation (IPR). Eligible participants will then be started on continuous positive airway pressure (CPAP) therapy and exposed to a multicomponent CPAP adherence intervention, beginning during IPR and extending for 3 months. Participants' CPAP use will be monitored, and input regarding the intervention will be sought from the participants, CPAP partners, and the research team implementing the intervention. Data from an initial group of study participants will be reviewed in meetings with the study team and a patient advisory board, and adaptations will be devised and then implemented within the next batch of study participants. Through this iterative process that includes input from important stakeholders, the behavioral intervention will be adapted for use among stroke patients.