REBOA in Nontraumatic OHCA (REBOA)
Cardiopulmonary Arrest
About this trial
This is an interventional treatment trial for Cardiopulmonary Arrest focused on measuring Advanced cardiopulmonary resuscitation (ACLS), Cardiopulmonary resuscitation (CPR), Resuscitative endovascular balloon occlusion of the aorta (REBOA)
Eligibility Criteria
Inclusion Criteria: Adult nontraumatic OHCA Witnessed arrest Arrival at ER from 9AM to 5PM (in each country) Exclusion Criteria: age below 20 years old or over 80 years old, traumatic cardiac arrest, those with unwitnessed cardiac arrest, pregnant patients, patients who have already achieved ROSC upon arrival at the emergency department pre-cardiac arrest cerebral performance category of 3-4 those showing evidence of cardiac arrest due to bleeding (such as gastrointestinal bleeding) those suspected of having aortic disease, such as dissection, intramural hematoma, or aneurysm, by bedside ultrasound performed immediately after ED arrival or have a previous history of aortic disease whose legal representative has requested termination of resuscitation efforts before study enrollment declared dead at scene before randomization Patients who meet the criteria for extracorporeal cardiopulmonary resuscitation (ECPR), and therefore the decision is made to perform ECPR, will not be enrolled. The ECPR criteria applies when all of the following criteria are met: pre-cardiac arrest CPC of 1-2, witnessed cardiac arrest with bystander CPR, ages between 20-70, initial shockable rhythm, ECMO pump-on available within 60 minutes of onset of cardiac arrest, and patients without end-stage diseases such as cancer, liver cirrhosis, or end-stage renal failure.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
No Intervention
Experimental
Control
REBOA
Patients allocated to this arm receives conventional resuscitative measures according to the 2020 AHA CPR Guidelines.
After enrollment and randomization, patients allocated to this arm receives REBOA in addition to conventional ACLS according to the 2020 AHA CPR guidelines. The common femoral artery is accessed with ultrasound guidance. A sheath catheter is inserted, followed by a REBOA catheter. The REBOA is ballooned with 20cc of normal saline or until resistance is felt.