Potassium-titanyl Phosphate (KTP) Laser vs KTP Laser and Ivermectin Cream for Facial Rosacea (KIR)
Rosacea
About this trial
This is an interventional treatment trial for Rosacea focused on measuring Rosacea, Laser, Ivermectin
Eligibility Criteria
Inclusion Criteria: Fitzpatrick skin type I-IV Presence of facial erythematous rosacea or mild papulopustular rosacea with permanent erythema Informed consent signed Exclusion Criteria: History of adverse events related to KTP laser therapy Pregnant or breastfeeding women Intention to become pregnant during the course of the study History of intolerance or allergic reaction to ivermectin 1% cream or one of the ingredients Ongoing treatment for skin cancer Ongoing treatment with strong inhibitors of P-glycoprotein (P-gp) and CYP3A4 (e.g., itraconazole, voriconazole, posaconazole, clarithromycin, cobicistat) Ongoing treatment with substances with a narrow therapeutic range whose excretion depends substantially on P-gp (e.g. digoxin, ciclosporin) Inability to understand the study content
Sites / Locations
- Department of dermatology, University Hospital Inselspital, Bern
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Laser and cream
Laser alone