Effects of Whole-body Vibration Therapy on Type 2 Diabetic Patients With and Without Polyneuropathy
Type 2 Diabetes, Diabetic Peripheral Neuropathy, Exercise
About this trial
This is an interventional supportive care trial for Type 2 Diabetes focused on measuring Type 2 diabetes mellitus, Diabetic Peripheral Neuropathy, whole body vibration, inflammation
Eligibility Criteria
Inclusion Criteria: Participants must stand and walk o without using an assistive device. Participants must have HbA1C level below 8.5 Participants must have a weight of less than 120 kg. Exclusion Criteria: T2DM patients with advanced cardiovascular, renal, hepatic disease T2DM patients with diabetic retinopathy or nephropathy T2DM patients with untreated hypertension, rhythm disorders, and those who have undergone bypass surgery T2DM patients with ischemic changes in the resting ECG T2DM patients with untreated hypoglycemia or orthostatic hypotension T2DM patients who are unable to walk independently, or use of canes, crutches or wheelchairs T2DM patients who have open ulcers or wounds on load-bearing surfaces T2DM patients with inflammatory rheumatic diseases such as rheumatoid arthritis T2DM patients with active infectious disease T2DM patients with high risk of thrombosis, those with deep vein thrombosis T2DM patients who carry a pacemaker, prosthesis, intrauterine device or metal implant, T2DM patients with a history of cancer T2DM patients with severe migraine, epilepsy, stroke or other neurological disorders, those who have undergone brain surgery T2DM patients with non-diabetic neuropathy due to reasons such as HIV, AIDS, alcohol, uremia T2DM patients with cognitive impairment T2DM patients who are on psychotropic or neurotoxic therapy T2DM patients with advanced balance problems T2DM patients who are pregnant or breastfeeding mothers T2DM patients who are organ transplant recipients T2DM patients with hernia T2DM patients with kidney or bladder stones T2DM patients who are exposed to mechanical vibration due to their job T2DM patients who received insulin therapy during their participation in the study
Sites / Locations
- Pamukkale University
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Placebo Comparator
T2DM with neuropathy + WBV
T2DM without neuropathy + WBV
T2DM with neuropathy + land exercise
Patients with type 2 Diabetes mellitus with neuropathy who will be trained by whole body vibration
Patients without type 2 Diabetes mellitus with neuropathy who will be trained by whole body vibration
Patients with type 2 Diabetes mellitus with neuropathy who will be trained on land