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Effect of Implementing Emergency Nursing Protocol About Oliguria and Anuria on Patients' Outcomes

Primary Purpose

Oliguria

Status
Not yet recruiting
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
Nursing protocol
Sponsored by
Hager AbdelNasser Hussein
About
Eligibility
Locations
Outcomes
Full info

About this trial

This is an interventional other trial for Oliguria

Eligibility Criteria

18 Years - 60 Years (Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria Diagnosis: Post renal oliguria and anuria for 12 hours. Investigations: serum creatinine < 2 mg. Exclusion Criteria Patients who refused participation in study. Patients who drained by PCN. Patients who dialysate > 1 session. Patients with GCS <12

Sites / Locations

    Outcomes

    Primary Outcome Measures

    Complications
    Electrolytes disturbances and renal failure

    Secondary Outcome Measures

    Full Information

    First Posted
    September 12, 2023
    Last Updated
    September 12, 2023
    Sponsor
    Hager AbdelNasser Hussein
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    1. Study Identification

    Unique Protocol Identification Number
    NCT06042868
    Brief Title
    Effect of Implementing Emergency Nursing Protocol About Oliguria and Anuria on Patients' Outcomes
    Official Title
    Effect of Implementing Emergency Nursing Protocol About Obstructive Anuria and Oliguria on Critically Ill Patients' Outcomes
    Study Type
    Interventional

    2. Study Status

    Record Verification Date
    September 2023
    Overall Recruitment Status
    Not yet recruiting
    Study Start Date
    September 2023 (Anticipated)
    Primary Completion Date
    September 2024 (Anticipated)
    Study Completion Date
    September 2024 (Anticipated)

    3. Sponsor/Collaborators

    Responsible Party, by Official Title
    Sponsor-Investigator
    Name of the Sponsor
    Hager AbdelNasser Hussein

    4. Oversight

    Studies a U.S. FDA-regulated Drug Product
    No
    Studies a U.S. FDA-regulated Device Product
    No

    5. Study Description

    Brief Summary
    This study is aim to evaluate the effect of implementing emergency nursing protocol of obstructive anuria and oliguria on critically ill patients' outcomes.
    Detailed Description
    Obstructive anuria is defined as a total cessation of diuresis or a volume of less than 200 ml /24 hours or 0 mL/12 h. Oliguria is defined as a urine output that is less than 400 mL/24 h or less than 17 mL/h, due to unilateral or bilateral blockage of a single anatomical or functional kidney. It is rapidly the cause of acute renal failure, endangering the vital prognosis in the short term and requiring emergency treatment in a specialized environment, whatever its etiology (Afifi R, et al., 2022). Obstructive anuria and oliguria constitutes a major cause for surgical acute kidney injury (AKI) due to several diseases as cervical cancer, urinary stone, bladder cancer, urinary tract stenosis, and iatrogenic causes. However, Obstructive anuria and oliguria management varies between each case; the treatment of choice is based on each patient's condition. We discovered that a proper management of obstructive anuria resulted in a low mortality rate as well as restoration of renal function in most patients (Wicaksono F, et al., 2021). Anuria /Oliguria is frequently observed in the perioperative period and may be the consequence of hypovolemia and/or pain, both triggering the sympathetic nervous system, which in turn lead to activation of the renin-angiotensin-aldosterone system with ensuing oliguria. However, oliguria may also represent a warning of deteriorating renal function, especially in critically ill patients (Vincent JL and et al., 2020). 2 There are many complications from anuria and oliguria as cardiovascular complications include congestive heart failure, pulmonary edema, and hypertension, mainly as a result of salt and water retention. Gastrointestinal complications as anorexia, nausea, vomiting and gastrointestinal bleeding. Neurologic complications as confusion and seizures may develop in the course of acute oliguria. Impaired defenses and responses against infection due to uremia and inappropriate use of antibiotics may contribute to the high degree of infectious complications. Percutaneous nephrostomy is an excellent initial procedure to relieve obstruction with minimal complications. The second choice is renal dialysis for deteriorated patients (Rachid M, et al., 2020). There is a critical role of nurse for taking history for oliguria and anuria as total volumes of urine in 24 h, color of urine, accompanying symptoms as (frequency, urgency and dysuria), special food or drugs as (nephrotoxic drugs, chemicals, eating raw fish guts); history of relevant diseases as (hemorrhoea, shock, heart failure, renal percussive pain, high fever, etc.) ; Past history including respiratory infection, angina, chronic nephritis, urinary calculus, prostate hyperplasia; travelling history as (epidemic hemorrhagic fever or epidemic area) should be pay attention. Critical care nurse must monitor hemodynamic parameters, signs of dehydration or fluid overload, fluids balances and duration of oliguria

    6. Conditions and Keywords

    Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
    Oliguria

    7. Study Design

    Primary Purpose
    Other
    Study Phase
    Not Applicable
    Interventional Study Model
    Parallel Assignment
    Masking
    None (Open Label)
    Allocation
    N/A
    Enrollment
    60 (Anticipated)

    8. Arms, Groups, and Interventions

    Intervention Type
    Other
    Intervention Name(s)
    Nursing protocol
    Intervention Description
    Emergency nursing protocol
    Primary Outcome Measure Information:
    Title
    Complications
    Description
    Electrolytes disturbances and renal failure
    Time Frame
    1year

    10. Eligibility

    Sex
    All
    Minimum Age & Unit of Time
    18 Years
    Maximum Age & Unit of Time
    60 Years
    Accepts Healthy Volunteers
    No
    Eligibility Criteria
    Inclusion Criteria Diagnosis: Post renal oliguria and anuria for 12 hours. Investigations: serum creatinine < 2 mg. Exclusion Criteria Patients who refused participation in study. Patients who drained by PCN. Patients who dialysate > 1 session. Patients with GCS <12
    Central Contact Person:
    First Name & Middle Initial & Last Name or Official Title & Degree
    Hager Abdel Nasser Hussein, Master degree at nursing
    Phone
    01142347873
    Email
    Hgogonono90@gmail.com

    12. IPD Sharing Statement

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