Effect of Implementing Emergency Nursing Protocol About Oliguria and Anuria on Patients' Outcomes
Primary Purpose
Oliguria
Status
Not yet recruiting
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
Nursing protocol
Sponsored by
About this trial
This is an interventional other trial for Oliguria
Eligibility Criteria
Inclusion Criteria Diagnosis: Post renal oliguria and anuria for 12 hours. Investigations: serum creatinine < 2 mg. Exclusion Criteria Patients who refused participation in study. Patients who drained by PCN. Patients who dialysate > 1 session. Patients with GCS <12
Sites / Locations
Outcomes
Primary Outcome Measures
Complications
Electrolytes disturbances and renal failure
Secondary Outcome Measures
Full Information
NCT ID
NCT06042868
First Posted
September 12, 2023
Last Updated
September 12, 2023
Sponsor
Hager AbdelNasser Hussein
1. Study Identification
Unique Protocol Identification Number
NCT06042868
Brief Title
Effect of Implementing Emergency Nursing Protocol About Oliguria and Anuria on Patients' Outcomes
Official Title
Effect of Implementing Emergency Nursing Protocol About Obstructive Anuria and Oliguria on Critically Ill Patients' Outcomes
Study Type
Interventional
2. Study Status
Record Verification Date
September 2023
Overall Recruitment Status
Not yet recruiting
Study Start Date
September 2023 (Anticipated)
Primary Completion Date
September 2024 (Anticipated)
Study Completion Date
September 2024 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor-Investigator
Name of the Sponsor
Hager AbdelNasser Hussein
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
5. Study Description
Brief Summary
This study is aim to evaluate the effect of implementing emergency nursing protocol of obstructive anuria and oliguria on critically ill patients' outcomes.
Detailed Description
Obstructive anuria is defined as a total cessation of diuresis or a volume of less than 200 ml /24 hours or 0 mL/12 h. Oliguria is defined as a urine output that is less than 400 mL/24 h or less than 17 mL/h, due to unilateral or bilateral blockage of a single anatomical or functional kidney. It is rapidly the cause of acute renal failure, endangering the vital prognosis in the short term and requiring emergency treatment in a specialized environment, whatever its etiology (Afifi R, et al., 2022).
Obstructive anuria and oliguria constitutes a major cause for surgical acute kidney injury (AKI) due to several diseases as cervical cancer, urinary stone, bladder cancer, urinary tract stenosis, and iatrogenic causes. However, Obstructive anuria and oliguria management varies between each case; the treatment of choice is based on each patient's condition. We discovered that a proper management of obstructive anuria resulted in a low mortality rate as well as restoration of renal function in most patients (Wicaksono F, et al., 2021).
Anuria /Oliguria is frequently observed in the perioperative period and may be the consequence of hypovolemia and/or pain, both triggering the sympathetic nervous system, which in turn lead to activation of the renin-angiotensin-aldosterone system with ensuing oliguria. However, oliguria may also represent a warning of deteriorating renal function, especially in critically ill patients (Vincent JL and et al., 2020).
2
There are many complications from anuria and oliguria as cardiovascular complications include congestive heart failure, pulmonary edema, and hypertension, mainly as a result of salt and water retention. Gastrointestinal complications as anorexia, nausea, vomiting and gastrointestinal bleeding. Neurologic complications as confusion and seizures may develop in the course of acute oliguria. Impaired defenses and responses against infection due to uremia and inappropriate use of antibiotics may contribute to the high degree of infectious complications. Percutaneous nephrostomy is an excellent initial procedure to relieve obstruction with minimal complications. The second choice is renal dialysis for deteriorated patients (Rachid M, et al., 2020).
There is a critical role of nurse for taking history for oliguria and anuria as total volumes of urine in 24 h, color of urine, accompanying symptoms as (frequency, urgency and dysuria), special food or drugs as (nephrotoxic drugs, chemicals, eating raw fish guts); history of relevant diseases as (hemorrhoea, shock, heart failure, renal percussive pain, high fever, etc.) ; Past history including respiratory infection, angina, chronic nephritis, urinary calculus, prostate hyperplasia; travelling history as (epidemic hemorrhagic fever or epidemic area) should be pay attention. Critical care nurse must monitor hemodynamic parameters, signs of dehydration or fluid overload, fluids balances and duration of oliguria
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Oliguria
7. Study Design
Primary Purpose
Other
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
60 (Anticipated)
8. Arms, Groups, and Interventions
Intervention Type
Other
Intervention Name(s)
Nursing protocol
Intervention Description
Emergency nursing protocol
Primary Outcome Measure Information:
Title
Complications
Description
Electrolytes disturbances and renal failure
Time Frame
1year
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
60 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria Diagnosis: Post renal oliguria and anuria for 12 hours. Investigations: serum creatinine < 2 mg. Exclusion Criteria Patients who refused participation in study. Patients who drained by PCN. Patients who dialysate > 1 session. Patients with GCS <12
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Hager Abdel Nasser Hussein, Master degree at nursing
Phone
01142347873
Email
Hgogonono90@gmail.com
12. IPD Sharing Statement
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Effect of Implementing Emergency Nursing Protocol About Oliguria and Anuria on Patients' Outcomes
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