Curcumin VS Photo-bio-modulation Therapy of Oral Mucositis in Pediatric Patients Undergoing Anti-Cancer Non-invasive Treatment
Oral Mucositis, Pediatric Cancer
About this trial
This is an interventional treatment trial for Oral Mucositis focused on measuring Curcumin, Photodynamic therapy, Pedology, Photo-bio-modulation, Oral Mucositis
Eligibility Criteria
Inclusion Criteria: patients in age group of 3 years to 15 years mucositis (categorized >1) based on the guidelines of WHO Toxicity Criteria must be able to open the mouth properly Exclusion Criteria: Patients with age less than 3 years and more than 15 years of age patients with systemic diseases
Sites / Locations
- Riyadh Elm UniversityRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Group A: Oral Mucositis
Group B: Oral Mucositis
Group A will be submitted to photodynamic therapy (Curcumin and red laser, λ450 nm) with 142 J/cm2, 100mW. The number of points will be calculated based on the size of lesion (1 laser shot per cm2 of lesion). The intervention will be repeated daily until cure of the oral mucositis was attained.
Group B (control group) will be submitted to low level (LL) laser therapy (λ660 nm) with 1J energy per point at 100mW power output for 10 seconds on daily basis until the lesion is clinically cured. The light will be applied perpendicular to the lesion on a continuous mode. The number of points will be calculated similarly as mentioned for patients included in Group A.