Brain Low-risk Aneurysm Stereotactic Radiosurgical Trial (BLAST)
Intracranial Aneurysm
About this trial
This is an interventional treatment trial for Intracranial Aneurysm focused on measuring brain aneurysm, radiosurgery, intracranial aneurysm
Eligibility Criteria
Inclusion Criteria: Medical imaging (CTA, MRA or digital substraction angiography) reveals the existence of an asymptomatic unruptured saccular anterior circulation intracranial aneurysm under 7 mm Advised by a vascular neurosurgeon to observe rather than undergo endovascular or microsurgical management Exclusion Criteria: Prior history of aneurysmal rupture Presence of symptoms that could be attributed to the aneurysm (severe headache, third cranial nerve deficits, or others) Imaging features deemed to increase rupture risk as evaluated by the treating physician Posterior circulation aneurysm Fusiform aneurysm Dissecting aneurysm Mycotic aneurysm Direct contact between the aneurysm and the optic pathways on medical imaging Prior coils or clips in the targeted aneurysm or any other aneurysm Patient unable to consent Patient unable or unlikely to comply with the follow-up schedule
Sites / Locations
- Centre Hospitalier Universitaire de SherbrookeRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
SRS group
Control group
Participants in the SRS group will receive the intervention described earlier, consisting of a Gamma Knife radiosurgery, and undergo the same follow-up exams (radiological and clinical) as participants of the control group.
The medical care will consist of observation for any element that may indicate an increased risk of rupture, like aneurysm growth or instability in shape.