Priming in Repetitive Transcranial Magnetic Stimulation in the Treatment of Obsessive Compulsive Disorder
Obsessive-Compulsive Disorder
About this trial
This is an interventional treatment trial for Obsessive-Compulsive Disorder focused on measuring priming, supplementary motor area, obsessive-compulsive disorder, transcranial magnetic stimulation
Eligibility Criteria
Inclusion Criteria: Being right-handed; Age between 18 and 60; Diagnose of OCD according to DSM-5; Score in YBOCS between 16 and 23; No change in dose prescription in the previous 3 months; Signature of informed consent term. Exclusion Criteria: Being pregnant; Having cognitive deficit; Diagnose of drug use disorder; In current psychotherapy (or interrupted in less than 3 months); Diagnose of severe Major Depression; Risk of suicide; Patients with metallic implants in the brain; Epileptics.
Sites / Locations
- Federal University of Paraíba,Department of PsychologyRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Sham Comparator
Active Priming (TMSr)
Sham Priming
To apply intervention, it will be used Repetitive Transcranial Magnetic Stimulation Model MagPro R20 (MagVenture Brazil, country Brazil) and the butterfly coil MCF-B70 (MagVenture Brazil, country Brazil). Each session will last around 20 minutes, and it will be used a 1 Hz frequency, 1200 pulses/day, with 100% of Motor Threshold, once a day, 5 days a week, for two consecutive weeks. Active Priming group participants will be previously stimulated for 10 minutes (20 trains of 5 seconds with intertrain interval of 25 seconds), with 6Hz frequency over Supplementary Motor Area, receiving 80% of Motor Threshold, with a total of 600 stimulations.
Sham Priming group participants will receive a placebo stimulation for ten minutes, with the same parameters and target area as the active group, they will hear the equipament noise and might feel any sensation in the scalp, but there won't be effective stimulation.