Azadirachta Indica (Neem) Extract as an Adjunct to Non-Surgical Periodontal Management
Periodontitis
About this trial
This is an interventional treatment trial for Periodontitis focused on measuring Periodontitis, Azadirachta Indica, Locally Delivery, TNF-α
Eligibility Criteria
Inclusion Criteria: Both males and females will be included in the age group of 20-55 years old. Patients diagnosed to have (Stage II or Stage III) periodontitis; (3-6 mm CAL, pocket depth ≤ 7 mm, mostly horizontal 15%-33% bone loss as assessed by preoperative radiographs with no tooth loss due to periodontitis). Patients free from systemic diseases according to the modified Burkett's health history questionnaire. Patients who can follow and maintain oral hygiene instructions. Patients who didn't perform any periodontal therapy in the last 6 months. Exclusion Criteria: Pregnant ladies or lactating mothers. Smokers. Patients with history of allergy against one of the components of neem. Asthmatic patients
Sites / Locations
- Faculty of Dentistry -Ain Shams University
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Azadirachta Indica
Non Surgical Periodontal Therapy
Azadirachta Indica (neem) gel are locally delivered to deepest part of the periodontal pocket by syringe with blunted tip gently and removed slowly in order not to harm the tissue for group 1 patients after phase 1 therapy by two weeks.
The patients will receive full mouth one stage debridement using ultrasonic scalers, manual scalers and curettes with oral hygiene instructions and education.