Capsule Microbiota Transplant Therapy for Hidradenitis Suppurativa

Inclusion Criteria: Able and willing to provide informed consent English speaking Age >= 18years of age Diagnosis of hidradenitis suppurativa by a dermatologist Women who are not post-menopausal (at least 12 months of non-therapy induced amenorrhea) or surgically sterile (e.g. absence of ovaries and/or uterus) must remain abstinent or use a highly effective form of birth control (e.g. oral contraception, transdermal patch, barrier, intrauterine device). Periodic abstinence and early withdraw are not acceptable methods Able to comply to study measures in the opinion of the investigator. Stable doses of all medications for 30 days prior to baseline Exclusion Criteria: Non-English speaking Refusal or inability to provide informed consent Planning on moving within 6 months from start of study Allergy to neomycin or vancomycin Anaphylactic food allergies Pregnancy, breastfeeding or planning pregnancy during study period (negative pregnancy test needed for persons of childbearing potential) Use of any topical or oral antibiotics within 30 days of randomization Use of any oral antibiotics within 90 days of randomization History of inflammatory bowel disease Extensive bowel resection (e.g., subtotal colectomy, substantial removal of small bowel) No major bowel surgery within 4 weeks prior to baseline or planned major surgery during the study period No active skin disease other than HS that could interfere with assessments