Initiative for Clinical Long-read Sequencing (IonGER)
Genetic Predisposition
About this trial
This is an interventional diagnostic trial for Genetic Predisposition focused on measuring Long-read sequencing, Rare diseases, Cancer preposition, Translate-NAMSE, German initiative for genomic medicine (genomDE)
Eligibility Criteria
Inclusion Criteria: Unclear molecular cause of the disease (retrospective cohort) Indication for genome diagnostics (prospective cohort; e.g. within the initiative for genomic medicine (genomDE) based on §64e SGB V) Suspected genetic cause of the disease Exclusion Criteria: - Missing informed consent of the patient or legal guardian
Sites / Locations
- University Hospital Tübingen
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Retrospective cohort
Prospective cohort
Subjects with unclear molecular cause of the disease. The subjects are clinically characterized in the context of outpatient/ inpatient standard care at the University Hospital Tübingen (UKT) or cooperating locations.
Subjects with indication for genome diagnostics (e.g. within the initiative for genomic medicine (genomDE) based on §64e German Social Code (SGB) Fifth Book (V) (SGB V).