Topical Sulfasalazine and Oral Lichen Planus
Oral Lichen Planus, Topical Sulfasalazine, Corticosteroids
About this trial
This is an interventional treatment trial for Oral Lichen Planus
Eligibility Criteria
Inclusion Criteria: - Patients with 30-65 years old Patents with atrophic OLP Exclusion Criteria: - Smokers pregnant or lactating ladies and Patients under topical or systemic steroids during the last two months Patients using lichenoid reaction-inducing drugs, Patients with positive hepatitis C virus (HCV) antibodies, diabetes and hypertension Patients having amalgam filling adjacent lesions will not also be included
Sites / Locations
- Faculty of Dentistry, Cairo University
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
study group (S group)
Control group (C group)
The patients will use topical sulfasalazine prepared by dissolving one tablet of commercially available in 100 ml of distilled water 4 times per day as a mouth wash combined with topical corticosteroids 4 times per day as a topical gel in an alternate sequence.
The 23 patients categorized as control group (C group) will receive topical corticosteroids gel only 4 times per day. The treatment regimen will be continued for 4 weeks.