Determination of Copper and Other Trace Elements in Serum Samples From Patients With Biliary Tract Cancers
Trace Element Deficiency
About this trial
This is an interventional other trial for Trace Element Deficiency focused on measuring metastatic biliary tract cancer, biomarkers, trace elements
Eligibility Criteria
Inclusion Criteria: aged ≥18 years cytologically or histologically verified biliary tract cancer no prior systemic therapy and no radiation therapy for advanced, inoperable or metastatic disease WHO performance status 0 - 2 (ECOG criteria) imaging diagnosis (CT of thoracic and abdominal organs) performed within 4 weeks prior to the first administration of systemic therapy disease measurable by RECIST or ECOG criteria signed Consent to Participate in Clinical Research form Exclusion Criteria: prior systemic treatment and radiation therapy for inoperable, metastatic disease WHO performance status > 2 (ECOG criteria) contraindications to immunotherapy (known immunodeficiency or active immunosuppressive therapy or active autoimmune disease requiring treatment) other malignancies, except cured basal cell or squamous cell carcinoma of the skin, in situ carcinoma of the cervix or other cured solid tumours without recurrence ≥ 3 years after treatment.
Sites / Locations
- Institute of Oncology LjubljanaRecruiting
Arms of the Study
Arm 1
Other
Open-label single arm of patients with metastatic BTCs
Systemic therapy: Identification of trace elements as novel predictive and prognostic biomarkers for response to systemic therapy in metastatic BTCs