Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplasty
Peri-implant Mucositis, Peri-Implantitis
About this trial
This is an interventional prevention trial for Peri-implant Mucositis focused on measuring Implantoplasty, Marginal bone level, Probing depth, Bleeding on probing
Eligibility Criteria
Inclusion Criteria: Aged 18-80 years In good general health, (at least ASA 2) Previously treated implants must have probing depths (PD) ≤ 4 mm Previously treated implants must have <50% bone loss around the implant of interest (assessed radiographically) Patients must have been treated previously for peri-implantitis with or without IP, with at least 1 thread or 2 mm of implant surface exposed in the oral cavity. Have little to no bacteria on the implant(s) of interest (modified Plaque Index of <1) by Day 0 Have healthy gums that do not bleed around the implant(s) of choice (modified Gingival index <1) by Day 0 Have evidence of stable bone levels around the treated implant for > 6 months Exclusion Criteria: Active infectious diseases of any kind. Medical conditions which require premedication prior to dental treatments/visits. Pregnant women or planning to become pregnant (self-reported). Patients with congenital or metabolic bone disorders (ie. osteoporosis, vitamin D deficiency, parathyroid disease, etc.) Current heavy smokers: Subjects who have smoked more than 1 pack/day within 6 months of study onset (self-reported) Subjects with co-morbid conditions (i.e., uncontrolled diabetes, cardiovascular disease, impaired kidney function, heart murmur, rheumatic fever, bleeding disorder, hepatitis, tuberculosis, HIV) that would affect the study outcome or interpretation of study results will be excluded. Concomitant medications: Subjects on significant concomitant drug therapy for systemic conditions (i.e., Chronic anti-inflammatory medication, antibiotics, anticoagulants, any medication initiated <3 months prior to the screening visit) will not be included in the study. Occasional short-term use (7-14 days) of analgesics or common cold medication is permitted. Such use of these medications will be reviewed and recorded by the Investigator.
Sites / Locations
- University of Pittsburgh School of Dental MedicineRecruiting
Arms of the Study
Arm 1
Experimental
Implants with history of peri-implantitis
Implant(s) treated previously for peri-implantitis with or without exposed polished surface, no PD > 4 mm and < 50% bone loss.