A Comparison of Safety and Immunogenicity of Rabies Pre Exposure Prophylaxis Regimen Between Gvt of India Approved and WHO Approved.
Vaccine Reaction
About this trial
This is an interventional prevention trial for Vaccine Reaction focused on measuring Immunogenicity
Eligibility Criteria
Inclusion Criteria: Healthy subjects willing to volunteer and sign written informed consent for the study. Subjects should be available for the follow-up period. Exclusion Criteria: Received Anti rabies vaccine or RIG or RMAb anytime in the past. Participation in any other clinical trial in the past three months. Severely immunocompromised subjects, pregnant and lactating women. Subjects with known history of allergy.
Sites / Locations
- Kempegowda Institute Of Medical Sciences Hospital and Research CenterRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Regimen 1
Regimen 2
WHO recommended PrEP Vaccination Schedule, 2 visits, 0.2ml 2 sites (0.1ml each site) on day 0 and day 7
Government of India currently recommended PrEP Schedule, 0.1ml 3 visits, on day 0, day 7 and day 28