REcruitment MAneuvers and Mechanical Ventilation Guided by EIT in pARDS (REMAV-EIT)
ARDS, Pediatric Respiratory Distress Syndrome, Respiratory Disease
About this trial
This is an interventional supportive care trial for ARDS focused on measuring Non invasive ventilation, electrical impedance tomography;
Eligibility Criteria
Inclusion Criteria: Intubated and mechanically ventilated children, ageing 1 months-5 years and meeting the PALICC definition for pediatric Acute Respiratory Distress Syndrome (pARDS) Informed Consent signed Exclusion Criteria: Patients with one or more of the following characteristics: Previous barotrauma (pneumothorax, pneumomediastinum or subcutaneous emphysema) Signs of intracranial hypertension Cyanotic congenital cardiac disease Dorso-lumbar pathologies or other bone pathologies associated with restrictive lung disease (such as scoliosis, kyphosis) Implantable devices not compatible with EIT (such as pace-makers and implantable cardioverter defibrillator) Controindication to positioning the esophageal catheter (surgery, esophageal stenosis)
Sites / Locations
- Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico MilanoRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Active Comparator
T0= Enrollment
T1= guided MV at the end of SRM trial
T2= 24 hours with EIT guided MV
mechanical ventilation will be set according to the standard of care criteria
EIT guided mechanical ventilation will be set
evaluation of mechanical ventilation after 24h EIT-guided ventilation