Assessment of the Applicability and Acceptability of an Algorithm to Guide the Prescription of 1st and 2nd Generation Cephalosporins as Part of Intraoperative Antibiotic Prophylaxis in Patients With a Declared Allergy to Penicillin (PROPHYLAL)
Adult Patients Who Declare an Allergy to Penicillin During Anaesthetic Consultation Without Any Allergy Work up That Could Confirm This Declaration, Good Comprehension of French Language
About this trial
This is an interventional prevention trial for Adult Patients Who Declare an Allergy to Penicillin During Anaesthetic Consultation Without Any Allergy Work up That Could Confirm This Declaration
Eligibility Criteria
Inclusion Criteria: Age >= 18 years; Patients with a good French understanding Who declare themselves allergic to penicillin and who have not benefit from an allergy work-up to explore their allergies and possible therapeutic alternatives; Requiring antibiotic prophylaxis with either first or second generation cephalosporins for elective or emergency surgery. Exclusion Criteria: Refusal to sign informed consent Patient under legal protection ; Pregnant women; Patient scheduled for surgery requiring first-line antibiotic prophylaxis with an agent other than first and second generation cephalosporins (such as amoxicillin/clavulanate or vancomycin) according to the recommendations of the French Society of Anaesthesia and Intensive Care (SFAR) in one of the investigating centres; Patient declaring an allergy to antibiotics other than penicillins. Not affiliated to a social security scheme
Sites / Locations
Arms of the Study
Arm 1
Arm 2
No Intervention
Experimental
usual care
use of a decision tree to guide antibiotic prophylaxis prescription