A Prospective Study on the Prediction Model of Para-aortic Lymph Node Metastasis

Inclusion Criteria: In 2018, the International Federation of Obstetrics and Gynecology (FIGO) stage was Ib3 IIA2-IVA; It was treated initially without surgical and chemotherapy. Squamous cell carcinoma, adenocarcinoma and adeno-squamous cell carcinoma were confirmed by histopathology. Pelvic MRI ± abdominal CT or MRI or PET/CT were performed before treatment. ECOG score:0 ~ 1. The expected survival time>6 months; There is no absolute contraindication of surgery and and chemoradiotherapy and the patients with good compliance. Exclusion Criteria: History of immune disease who need to take immunosuppressive drugs. History of serious mental illness and brain functional disorder. Other malignancies were diagnosed within five years or needed treatments. Those who are unable or unwilling to accept surgical treatment/sign informed consent/comply with research requirements. Without surgical conditions: 1) Chronic renal insufficiency or renal failure; 2) Liver insufficiency; 3)Chronic lung disease with restrictive respiratory dysfunction; 4) Cardiac dysfunction (patients with relative and absolute contraindications to surgery after consultation by cardiac physicians. Patients who cannot understand the research regimen and refuse to sign the informed consent form. Other concomitant diseases or special conditions seriously endanger the patient's health or interfere with the trial.