VK2735 for Weight Management Phase 2 (VENTURE)

Inclusion Criteria: Age ≥18 years of age at the time of signing the informed consent Body mass index (BMI) ≥30 kg/m2 OR ≥27 kg/m2 with at least one weight-related co-morbid condition (treated or untreated), and BMI <50 kg/m2 Exclusion Criteria: History of or current clinically significant medical or psychiatric disorder that, in the opinion of the Investigator, does not support study participation Self-reported body weight change of 5% or more within 3 months of screening Current or past diagnosis of diabetes mellitus (including type 1, type 2, gestational) Current or past diagnosis of chronic pancreatitis Calcitonin ≥20 ng/L measured by central laboratory at screening (individuals with elevated calcitonin at initial screening may be re-screened) Any GLP-1 receptor agonist or GLP-1/GIP dual agonist within 6 months of Screening Any prescription or over-the-counter medications intended for weight loss within 6 months of screening