Therapeutic Use of rTMS in Pediatric ASD and ADHD Cohorts
Autism Spectrum Disorder, ADHD, Neurodevelopmental Disorders
About this trial
This is an interventional treatment trial for Autism Spectrum Disorder focused on measuring TMS, NEUROMODULATION, ASD, ADHD, NEUROSTIMULATION, COGNITION, EXECUTIVE FUNCTIONS, DLPFC
Eligibility Criteria
Inclusion Criteria: Patients must have received a diagnosis of "ASD" or "ADHD" according to the Diagnostic and Statistical Manual of Mental Disorder-Fifth edition. Patients must be older than 6-7 years of age, to obtain their collaboration easily Exclusion Criteria: presence of known neurological or genetic conditions that are known to affect brain function and structure (i.e. brain tumors, X-fragile, tuberous sclerosis, etc.). prescription of psychoactive medication(s) less than 4 weeks prior to joining the study. medical history of head trauma associated with prolonged loss of consciousness. presence of epilepsy, or history of previous epilepsy, seizures, and repeated febrile seizures. presence of comorbidity with psychosis disorder. presence of known endocrine, cardiovascular, pulmonary, liver, kidney, or other medical diseases. vision and auditory impairment. presence of diagnosed chronic or acute inflammation and/or infection. lack of consent.
Sites / Locations
- Neuropsychiatric Unit for Child and Adolescent, at General Hospital "Riuniti" of Foggia, University of FoggiaRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Active Comparator
Sham Comparator
Active Comparator
Sham Comparator
Active ASD group
Sham ASD group
Active ADHD group
Sham ADHD group
The rTMS will be administered 18 times, twice per week, with the following stimulation parameters: 1.0 Hz frequency, 90% MT, 180 pulses per session with 9 trains of 20 pulses each with 20-30s intervals between the trains.
18 rTMS sessions will be administered, placing the coil perpendicular to the scalp of the stimulation site, to avoid stimulation.
The rTMS will be administered 18 times, twice per week, with the following parameters: 5-10 Hz frequency, 90% MT, 180 pulses per session with 9 trains of 20 pulses each with 20-30 s intervals between the trains.
18 rTMS sessions will be administered, placing the coil perpendicular to the scalp of the stimulation site, to avoid stimulation.