Assessment of Laryngopharyngeal Sensation: Cancer Survivor Cohort
Presbylarynx, Aspiration, Spasmodic Dysphonia
About this trial
This is an interventional device feasibility trial for Presbylarynx focused on measuring Cancer survivors, Previous cancer treatment, Laryngopharyngeal disorders
Eligibility Criteria
Inclusion Criteria: Age <=18 years. Individuals without a laryngopharyngeal disorder (health controls) or with a laryngopharyngeal disorder. Laryngopharyngeal disorder includes but is not limited to: presbylarynx, aspiration; spasmodic dysphonia; globus pharynges; vocal fold paralysis; iatrogenic injury to the larynx; muscle tension dysphonia; neurogenic dysphagia; laryngeal sensory neuropathy; and laryngopharyngeal disorders resulting from prior radiation therapy in individuals with a history of head and neck cancer who have completed radiation therapy as primary or adjuvant cancer treatment Ability and willingness to comply with study procedures. Ability to understand a written informed consent document, and the willingness to sign it. Exclusion Criteria: Non-English speaking. Laryngopharyngeal structures are not accessible on exam. Known contraindication to any study-related procedure, or history of being unable to tolerate laryngoscopy. Vocal fold immobility or severe hypomobility on adduction. For head and neck cancer survivors only: Currently undergoing radiation therapy for head and neck cancer (i.e., primary/adjuvant radiation therapy treatment plan is not yet completed).
Sites / Locations
- University of California, San Francisco
Arms of the Study
Arm 1
Experimental
Cancer Survivors
Participants will attend a single 15-30 minute study session during which they will answer questionnaires (5-10 minutes) and undergo laryngopharyngeal sensory testing (10-20 minutes). There will be up to 2 years of medical record follow up after completing the main study.